Professor Toru Miyazaki has discovered a potential trigger for feline CKD:

It is well known that cats are profoundly more susceptible to and more often die from chronic kidney disease (CKD) than other animals
According to Japanese immunologist Toru Miyazaki, a professor at the University of Tokyo’s Graduate School of Medicine: 
“The AIM molecules that circulate in the blood are bound to IgM [immunoglobulin M] antibodies,” Miyazaki explains. “When there’s waste matter or debris that needs to be removed, the AIM protein launches from the IgM like a jet fighter from an aircraft carrier. It attaches to the problematic debris, flagging it so that the cleansing process can begin.

We found that in cats, the AIM is too tightly bound to the IgM to launch, and as a result, the debris doesn’t get cleaned up.” 
When AIM and IgM fail to dissociate (become unattached), the dead cells and debris in the cat's system are not effectively destroyed and cleaned up. This is why, according to Miyazaki, many cats end up developing kidney problems and renal diseases.


What is AIM30 ?

Professor Miyazaki has collaborated with an pet food producer and a pharmaceutical company in Japan to develop a food+drug companion therapy called "AIM30." This therapy aims to prevent and treat CKD (Chronic Kidney Disease) in cats.
AIM30 contains the amino acid A-30 to help the AIM do the kidney cleanup. It is the A-30's job to disassociate the AIM from the IgM and activate it. The best way to prevent feline CKD is to fix the root problem.


Reference:
https://www.nature.com/articles/srep35251?ref=barkandwhiskers.com